Lots of dance at this time of year with many friends having their shows. Bolt by Jeryl Palana’s Art on Earth company started off Asian American Month with a focus on three women choreographers. I had a blast watching them and moderating the Q&A afterwards. Such wonderful artists! And...
Human ApoE has three isoforms differing only by 1 amino acid substitution at either position 112 or 158, resulting in E2, E3, or E4 alleles. Even 1 copy of the E4 allele raises your risk for Alzheimer’s Disease 4-fold and if you’re unfortunate enough to possess an E4 allele...
What are HDLs? Are they cardioprotective or harmful? How do statins affect them? How do they impact immune cells? Join us for this episode of vlmd rounds and learn about HDLs–the truth may surprise you.
We’ll look at the Renin-Angiotensin-Aldosterone System (RAAS) and its impact on different tissues in the body with an emphasis on the brain. Find out how RAAS activation damages your body and what to do about it.
BCAAs have been implicated in obesity, insulin resistance, worsening heart failure and liver disease. Should we be cutting down on BCAAs? Are plant protein sources better for you? Why do I consider this topic a can of worms (which, incidentally, are a great source of protein and BCAAs!)...
It’s important to know when ketones are good for you and when they are bad for you. What do we know about heart function on chronic ketone body exposure? What do ketones have to do with mTORC1 and v-ATPases? How did amino acids sneak into this episode??? Check out Episode 30 of vlmd...
Many of my patients are startled at their first DXA body composition reports. “How can this be? I was 8% body fat at the gym!” That’s because their personal trainer likely used a handheld bioimpedance device to measure their body composition. Those devices are notoriously inaccurate. If...
April is National Poetry Month. I woke up on April 2nd and that was my first thought. My second thought was, what poem should I feature in my newsletter? Without prompting, Hölderlin’s Patmos came to mind. Hölderlin??? I hadn’t read him in years. I tried to think of another...
We’re looking at heart metabolism in this episode. What fuels feed the heart? Do those substrates change in insulin resistance and if so, in what way? We’ll explore the basics of cardiac metabolism in this episode.
Brain Metabolism: What happens to Glucose in the Brain The Brain is only 2% of body mass and consumes over 20% of the body’s glucose. How does it handle the glucose? Why is it that neurons take up 80-90% of the total energy in the brain but don’t take up most of the glucose...
